BioStacksApigenin and sleep
Apigenin plays a supporting role in sleep. Apigenin is a flavonoid found in chamomile that acts as a mild GABA-A receptor ligand. Clinical evidence is almost entirely for chamomile extract, not isolated apigenin. In clinical studies, apigenin may support sleep quality through mild sedative effects.
Effective dosing
Most evidence supports 50–200 mg of apigenin daily. 50 mg isolated apigenin is the popular protocol; clinical evidence is primarily for chamomile extract (500-1500 mg, which delivers ~5-15 mg apigenin). Products below this range may not deliver meaningful results.
What the research says
The clinical evidence for apigenin in sleep is limited. No clinical trials for isolated apigenin at supplement doses; evidence is for chamomile extract only Learn more
