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Best Inositol for Hormones
Top 28 products ranked · Reviewed May 2026 · 2000–4000 mg clinical dose
Why Inositol for Hormones
Inositol plays a key role in hormones. The predominant naturally occurring isomer of inositol. Studied for PCOS, insulin sensitivity, mood, and anxiety.
What dose to look for
Clinical studies typically use 2000–4000 mg of inositol. Myo-inositol supplement range; higher doses used for mood, hormonal, and metabolic support. Products below this range may not deliver meaningful results.
What the research says
Inositol has moderate clinical evidence for hormones benefits. Several clinical trials for PCOS and insulin sensitivity, but limited to specific populations Learn more
Clinical research on Myo-Inositol
MODERATE-STRONG for PCOS insulin/ovulation — NOT a testosterone booster · 2,000–4,000 mg/day (often with ~400 mcg folic acid)
- •2024 guideline meta-analysis (30 trials, 19 pooled) found benefits for some metabolic markers and a signal for ovulation in PCOS, but called overall evidence 'limited and inconclusive'. PubMed
- •RCT in overweight PCOS women: 2 g/day myo-inositol significantly lowered LH, the LH:FSH ratio, insulin, and HOMA-IR vs folic-acid placebo over 12 weeks — the insulin-androgen mechanism in action. PubMed
- •Cochrane review of 13 trials rated the PCOS fertility (live-birth) evidence low-to-very-low quality — uncertain whether myo-inositol improves live birth or pregnancy vs standard care.
- •RCT in postmenopausal metabolic-syndrome women: 4 g/day for 12 months improved HOMA-IR, blood pressure, and lipids vs diet alone — benefits cluster in insulin-resistant populations. PubMed