BioStacks

Best Selenium for General Health

Top 10 products ranked

Last reviewed May 2026

Clinical dose: 100–200 mcg

Why Selenium for General Health

Selenium plays a supporting role in general health. Essential component of selenoproteins including glutathione peroxidase (antioxidant defense) and deiodinases (thyroid hormone activation). Selenomethionine is the most bioavailable supplemental form, while sodium selenite is inorganic and less efficiently absorbed.

What dose to look for

Clinical studies typically use 100–200 mcg of selenium. Common supplement dose; UL is 400 mcg/day. Products below this range may not deliver meaningful results.

What form to look for

Avoid sodium selenite — inorganic, lower retention. Look for selenomethionine for better absorption.

What the research says

Selenium has strong clinical evidence for general health benefits. SELECT trial (35,000+ men) found no cancer prevention benefit; essential for thyroid via selenoproteins Learn more